Book description
This second edition of a bestselling textbook offers an instructive and
comprehensive overview of our current knowledge of biocatalysis and
enzyme technology.
The book now contains about 40% more printed content. Three
chapters are completely new, while the others have been thoroughly
updated, and a section with problems and solutions as well as new case
studies have been added.
Following an introduction to the history of enzyme
applications, the text goes on to cover in depth enzyme mechanisms and
kinetics, production, recovery, characterization and design by protein
engineering. The authors treat a broad range of applications of
soluble and immobilized biocatalysts, including wholecell
systems, the use of non-aqueous reaction systems, applications in
organic synthesis, bioreactor design and reaction engineering. Methods
to estimate the sustainability, important internet resources and their
evaluation, and legislation concerning the use of biocatalysts are
also covered.
Born in 1941, Klaus Buchholz studied chemistry at the
universities of Saarbrücken und Heidelberg, graduating in 1967. In
1969 he received his PhD from the TU Munich, after which he worked as
a researcher at Dechema e. V. in Frankfurt/Main until 1982. In 1981 he
qualified as a professor at the TU Braunschweig, where he then became
department head at the Institute for Agricultural Technology and Sugar
Industry. From 1988 onwards he was the provisional Head of the
Institute, before becoming Professor for Technology of Carbohydrates
at the Institute for Technical Chemistry in 1991. His main research
areas include biocatalysts, enzymatic processes for the modification
and synthesis of saccharides, environmental biotechnology, flow bed
reactors with immobilized biocatalysts, and the synthesis of
saccharide polymers.
Volker Kasche, born in 1939, studied chemistry, mathematics,
and physics at the University of Uppsala, Sweden, receiving his degree
in 1964. This was followed by a year as a NATO research fellow at
Brandeis University, USA. He received his doctorate from the
University of Uppsala in 1971, and in 1973 became Professor for
Physical Biology at the University of Bremen, Germany. He has been
Professor for Biotechnology at the TU Hamburg-Harburg, Germany, since
1986, focusing his research on fundamentals of equilibrium and
kinetically controlled reactions catalyzed by free and immobilized
hydrolases, the production, post-translational processing and
purification of penicillin amidases and serine peptidases by affinity
chromatography, as well as fundamentals of mass transfer in
chromatography and enzyme technology.
Born in 1964, Uwe Bornscheuer studied chemistry at the
University of Hanover, Germany, where he graduated in 1990. After
receiving his PhD in 1993 from the Institute of Technical Chemistry at
the same university, he spent a postdoctoral year at the University of
Nagoya, Japan. He then joined the Institute of Technical Biochemistry,
University of Stuttgart, Germany, where he qualified as a professor in
1998. He has been Professor for Technical Chemistry &
Biotechnology at the University of Greifswald, Germany since 1999.
Professor Bornscheuer's main research interest is the application of
enzymes in the synthesis of optically active compounds and in lipid modification.
