Book description
The chemistry of heterocycles is an important branch of organic
chemistry. This is due to the fact that a large number of natural products,
e. g. hormones, antibiotics, vitamins, etc. are composed of heterocyclic
structures. Often, these compounds show beneficial properties and are
therefore applied as pharmaceuticals to treat diseases or as
insecticides, herbicides or fungicides in crop protection. This volume
presents important agrochemicals. Each of the 21 chapters covers in a
concise manner one class of heterocycles, clearly structured as follows:
* Structural formulas of most important examples (market products)
*Short background of history or discovery
* Typical syntheses of important examples
* Mode of action
* Characteristic biological activity
* Structure-activity relationship
* Additional chemistry information (e. g. further transformations,
alternative syntheses, metabolic pathways, etc.)
* References
A valuable one-stop reference source for researchers in academia and
industry as well as for graduate students with career aspirations in the
agrochemical chemistry. Clemens Lamberth is a senior team leader in
the crop protection research department of Syngenta AG, Switzerland. He
studied chemistry at the Technical University of Darmstadt, Germany,
where he obtained his Ph. D. under the supervision of Prof. Bernd Giese
in 1990. Subsequently, he spent one and a half years as a postdoctoral
fellow in the group of Prof. Mark Bednarski at the University of
California at Berkeley, U. S.A. In 1992 Clemens Lamberth joined the
agrochemical research department of Sandoz Agro AG, Switzerland, which
is today, after two mergers, part of Syngenta Crop Protection AG. Since
20 years he is specialized in fungicide discovery. He was the organizer
of the two-day session 'New Trends for Agrochemicals' at the 2nd EUCHEMS
congress in Torino 2008. He is the author of 46 publications and 56
patents and the inventor of Syngenta's fungicide mandipropamid (Revus?, Pergado?).
Jürgen Dinges obtained his M. S. degree in organic chemistry at the
Technical University in Darmstadt, Germany in 1988. He then joined the
group of Prof. Frieder W. Lichtenthaler at the same University, where he
received his Ph. D. degree in organic chemistry and chemical engineering
in 1991. After being awarded a Feodor-Lynen scholarship from the
Humboldt foundation, he spent 18 months as a postdoctoral fellow in the
group of Prof. William G. Dauben at the University of California at
Berkeley, U. S.A. In 1993, Jurgen Dinges joined the department for
biochemistry at Syntex, U. S.A. and since 1995 he is working in the
pharmaceutical research department at Abbott Laboratories, U. S.A. In
2009, he was a guest editor for Current Topics in Medicinal Chemistry
for a special issue on Parkinson?s disease. He is an author of 17
publications and 23 patents and a co-inventor of more than 10 clinical
drug development candidates.
