Book description
This sequel to the highly successful and much appreciated "Modern
Aldol Reactions" continues to provide a systematic overview of
methodologies for installing a required configuration during an aldol
addition step, but shifts the focus so as to cover the latest developments.
As such, it presents a set of brand new tools, including vinylogous
Mukaiyama-aldol reactions, substrate-controlled aldol reactions and
asymmetric induction in aldol additions. Furthermore, novel developments
in existing stereoselective aldol additions are described, such as the
deployment of supersilyl groups or organocatalyzed aldol additions.
Throughout, all of these methodologies are presented in the context of
their deployment in total synthesis of natural products.
Born in 1950, Rainer Mahrwald studied chemistry at MLU Halle and
subsequently joined the "Manfred von Ardenne" Research
Institute in Dresden, where he led the synthetics group. He gained his
doctorate under G. Wagner in Leipzig in 1979, and went on to the
Institute of Organic Chemistry at the Academy of Science in Berlin,
where he remained until 1990. Following a stay at the
Philipps-University in Marburg, Dr. Mahrwald qualified as a lecturer at
the Humboldt University Berlin, where he is now full professor.