Book description
Completely revised to reflect the developments in this fast-changing
field, this new edition features 35 % new content. It retains the
interdisciplinary approach that elegantly combines the chemistry and
engineering involved to describe the conception and improvement of
chromatographic processes. It also covers recent advances in preparative
chromatographic processes for the separation of "smaller"
molecules using standard laboratory equipment as well as the detailed
conception of industrial chemical plants. The increase in
biopharmaceutical substances is reflected by new and revised chapters on
different modifications of continuous chromatography as well as
ion-exchange chromatography and other separation principles widely used
in biochromatography.
Following an introductory section on the history of chromatography, the
current state of research and the design of chromatographic processes,
the book goes on to define the general terminology. There then follow
sections on stationary phases, selection of chromatographic systems and
process concepts. A completely new chapter deals with engineering and
operation of chromatographic equipment. Final chapters on modeling and
determination of model parameters as well as model based design,
optimization and control of preparative chromatographic processes allow
for optimal selection of chromatographic processes.
Essential for chemists and chemical engineers in the chemical,
pharmaceutical, and food industries.
Professor Schmidt-Traub was Professor for Plant and Process Design at
the Department of Biochemical and Chemical Engineering, University of
Dortmund, Germany until his retirement in 2006. He is still active in
the research community and his main areas of research focus on
preparative chromatography, down stream processing, integrated
processes, plant design and innovative energy transfer. Prior to his
academic appointment, Prof. Schmidt-Traub gained 15 years of industrial
experience in plant engineering.
Prof. Seidel-Morgenstern is the Director of the Max Planck Institute for
Dynamics of Complex Technical Systems, Magdeburg, Germany and holds the
Chair in Chemical Process Engineering at the
Otto-von-Guericke-Universitat, Magdeburg, Germany. He received his Ph.
D. in 1987 at the Institute of Physical Chemistry of the Academy of
Sciences in Berlin. From there he went on to work as postdoctoral fellow
at the University of Tennessee, Knoxville, USA. In 1994 he finished his
habilitation at the Technical University in Berlin. His research is
focused on New Reactor Concepts, Chromatographic Reactors, Membrane
Reactors, Adsorption and Preparative Chromatography and Separation of
Enantiomers amongst others.
Dr. Michael Schulte is Senior Director Emerging Businesses Energy at
Merck KGaA Performance Materials, Darmstadt, Germany. In his Ph. D.
thesis at the University of Munster, Germany he developed new chiral
stationary phases for chromatographic enantioseparations. In 1995 he
joined Merck and has since then been responsible for research and
development in the area of preparative chromatography, including the
development of new stationary phases, new separation processes and the
implementation of Simulated Moving Bed-technology at Merck. In his
current position one of his areas of research is the use of Ionic
Liquids for separation processes.
