Book description
This is the fourth of five books in the Amino Acids, Peptides and
Proteins in Organic Synthesis series.
Closing a gap in the literature, this is the only series to cover
this important topic in organic and biochemistry. Drawing upon the
combined expertise of the international "who's who" in amino
acid research, these volumes represent a real benchmark for amino acid
chemistry, providing a comprehensive discussion of the occurrence,
uses and applications of amino acids and, by extension, their
polymeric forms, peptides and proteins.
The practical value of each volume is heightened by the inclusion of
experimental procedures.
The 5 volumes cover the following topics:
Volume 1: Origins and Synthesis of Amino Acids
Volume 2: Modified Amino Acids, Organocatalysis and Enzymes
Volume 3: Building Blocks, Catalysis and Coupling Chemistry
Volume 4: Protection Reactions, Medicinal Chemistry, Combinatorial Synthesis
Volume 5: Analysis and Function of Amino Acids and Peptides
The fourth volume in this series is structured in three main
sections. The first section is about protection reactions and amino
acid based peptidomimetics. The second, and most extensive, part is
devoted to the medicinal chemistry of amino acids. It includes, among
others, the chemistry of alpha- and beta amino acids, peptide drugs,
and advances in N- and O-glycopeptide synthesis. The final part deals
with amino acids in combinatorial synthesis. Methods, such as phage
display, library peptide synthesis, and computational design are described.
Originally planned as a six volume series, Amino Acids, Peptides
and Proteins in Organic Chemistry now completes with five
volumes but remains comprehensive in both scope and coverage.
Further
information about the 5 Volume Set and purchasing details can be
viewed here.
Andrew Hughes
is a reader and Head of the Department of Chemistry, La Trobe
University, Melbourne, Australia. He obtained his degrees from the
University of Western Australia. Post-doctoral appointments at the
University of Cambridge starting 1989 included 3 years working with
Professor Andrew Holmes before joining Professor Steven Ley's group in
1993. While at Cambridge he was appointed the Shell Research Fellow at
Robinson College.
