Book description
Von Willebrand Disease: Basic and Clinical Aspects
provides an insight into all aspects of the condition. Since its
discovery, von Willebrand disease has been extensively studied and the
causative factor deficiency, the understanding of the condition and its
treatment has greatly improved. This book summarizes recent research and
will help to optimize the management of patients with von Willebrand
disease.
This valuable book describes the important and complex role
of von Willebrand factor in hemostasis and thrombosis. In addition to
the current understanding of its molecular biology, this book gives
particular focus to the association between genetic variants of von
Willebrand factor and different von Willebrand disease phenotypes. It
also reviews the important area of the obstetric and gynecological
manifestations of von Willebrand disease, as well as the treatment of
acute bleeding.
Written by an international team of contributors it describes the
progress in, and difficulties of diagnosing phenotypes and genotypes.
Molecular diagnosis of type 1, type 2 and its subgroups, and type 3
von Willebrand disease are presented as well as discussion of the
potential future role of gene therapy.
Von Willebrand Disease: Basic and Clinical Aspects is a
valuable resource for hematologists in practice and in training, and
specialists in thrombosis and hemostasis.
Augusto B. Federici, University of Milan, Milan, Italy
Christine A. Lee, Oxford Haemophilia & Thrombosis Centre,
Oxford, UK
Erik E. Berntorp, Lund University, Malmö, Sweden
David Lillicrap, Queen's University, Kingston, ON, Canada
Robert R. Montgomery, Medical College of Wisconsin; Milwaukee,
WI, USA
