Book description
Steroid dimers are an important group of compounds produced by
various marine organisms, and also synthesized in the laboratories.
This group of compounds possesses various pharmacological and
biological properties, and can also be used to create “molecular
umbrellas” for drug delivery.
Steroid Dimers: Chemistry and Applications in Drug Design and
Delivery provides an up-to-date overview on the chemistry and
applications of steroid dimers of natural and synthetic origins. The
book includes easy-to-follow synthetic protocols for various classes
of important dimeric steroids, source details, valuable spectroscopic
data and depiction of unique structural features of natural steroidal
dimers, and the Structure-Activity-Relationships (SARs) of some
pharmacologically active dimeric steroids. Topics covered include:
- introduction to steroid dimers
- synthesis and chemistry of noncyclic and cyclic steroid dimers
- naturally occurring steroid dimers - cephalostatins, ritterazines
and crellastatins
- biological and pharmacological functions of steroid dimers and
their application in drug design and discovery
- steroid dimers as “molecular umbrellas” for drug delivery
Steroid Dimers: Chemistry and Applications in Drug Design and Delivery
is an essential guide to this important class of natural and synthetic
compounds for researchers and students of natural products chemistry and
biochemistry, synthetic organic and medicinal chemistry, and drug
design, discovery and delivery.
