Book description
An authoritative look at the application of chemical biology in
drug discovery and development
Based on the award-winning Wiley Encyclopedia of Chemical
Biology published in 2008, this book explores the role of chemical
biology in drug discovery and development. The first part of the book
reviews key principles and techniques used in the design and
evaluation of drug candidates. The second part elucidates biological
mechanisms of certain diseases, illuminating approaches to investigate
and target these diseases.
Comprising carefully selected reprints from the Encyclopedia
as well as new contributions from leading scholars in the field, this
book provides researchers in academia and industry with important
information to aid in the development of novel agents to treat
disease. Self-contained articles cover a variety of essential topics, including:
- The design, development, and optimization of drug candidates
- The pharmacokinetics and properties of drugs
- Drug transport and delivery
- Natural products and natural product models as pharmaceuticals
- Biological mechanisms underlying health and disease
- Treatment strategies for a range of diseases, from HIV to schizophrenia
Chemical Biology is a top-notch guide and reference for anyone
working in the areas of drug discovery and development, including
researchers in chemical biology and other fields such as biochemistry,
medicine, and pharmaceutical sciences.
NATANYA CIVJAN, PhD, is a freelance editor with a doctorate in
biochemistry. Formerly with John Wiley & Sons, she developed and
edited the Wiley Encyclopedia of Chemical Biology and was part
of the team responsible for the Wiley Interdisciplinary
Reviews, which won top prizes in publishing from the American
Publishers Awards for Professional and Scholarly Excellence.
