Book description
Reverse genetics, the genetic manipulation of RNA viruses to create a
wild-type or modified virus, has led to important advances in our
understanding of viral gene function and interaction with host cells.
Since many severe viral human and animal pathogens are RNA viruses,
including those responsible for polio, measles, rotaviral diarrhoea
and influenza infections, it is also an extremely powerful technique
with important potential application for the prevention and control of
a range of human and animal viral diseases.
Reverse Genetics of RNA Viruses provides a comprehensive
account of the very latest developments in reverse genetics of RNA
viruses through a wide range of applications within each of the core
virus groups including; positive sense, negative sense and double
stranded RNA viruses. Written by a team of international experts in
the field, it provides a unique insight into how the field has
developed, what problems are being addressed now and where
applications may lead in the future. It will prove invaluable to
bioscience, medical and veterinary students, those starting research
in this area as well as other researchers and teachers needing to
update their knowledge of this fast-moving field.
- An authoritative, comprehensive overview of reverse genetics in
RNA Viruses.
- Includes numerous examples of cutting- edge applications of
reverse genetics within each of the RNA viral groups.
- Written by a team of international experts, including some of the
leading researchers in the field.
