Book description
Integrates solid-phase organic synthesis with palladium chemistry
The Wiley Series on Solid-Phase Organic Syntheses keeps researchers
current with major accomplishments in solid-phase organic synthesis,
providing full experimental details. Following the validated, tested,
and proven experimental procedures, readers can easily perform a broad
range of complex syntheses needed for their own experiments and
industrial applications. The series is conveniently organized into
themed volumes according to the specific type of synthesis.
This second volume in the series focuses on palladium chemistry in
solid-phase synthesis, exploring palladium catalysts and reactions,
procedures for preparation and utilization, ligands, and linker
reactions. The first part of the volume offers a comprehensive
overview of the field. Next, the chapters are organized into three parts:
- Part Two: Palladium-Mediated Solid-Phase Organic Syntheses
- Part Three: Immobilized Catalysts and Ligands
- Part Four: Palladium-Mediated Multifunctional Cleavage
Each chapter is written by one or more leading international experts
in palladium chemistry. Their contributions reflect a thorough
examination and review of the current literature as well as their own
first-hand laboratory experience. References at the end of each
chapter serve as a gateway to the field's literature.
The introduction of palladium-mediated, cross-coupling reactions more
than thirty years ago revolutionized the science of carbon-carbon bond
formation. It has now become a cornerstone of today's synthetic
organic chemistry laboratory. With this volume, researchers in organic
and medicinal chemistry have access to a single resource that explains
the fundamentals of palladium chemistry in solid-phase synthesis and
sets forth clear, step-by-step instructions for conducting their own
syntheses.
PETER J. H. SCOTT is an Assistant Professor in the Department
of Radiology at the University of Michigan Medical School. Dr. Scott
edited Linker Strategies in Solid-Phase Organic Synthesis (also
from Wiley) and is the Series Editor for both the Wiley Series on
Radiochemical Syntheses and the Wiley Series on Solid-Phase Organic Syntheses.
