Book description
This book will describe fundamentals and recent developments in the
area of Self-Assembled Supramolecular Architecture and their relevance
to the understanding of the functionality of membranes as delivery
systems for active ingredients. As the heirarchial architectures
determine their performance capabilities, attention will be paid to
theoretical and design aspects related to the construction of lyotropic
liquid crystals: mesophases such as lamellar, hexagonal, cubic, sponge
phase micellosomes. The book will bring to the reader mechanistic
aspects, compositional considerations, transition within phases,
solubilization capacities, drug entrapment and release mechanisms and
transmembrane, transdermal, and other transport phenomena. It will
stress the importance of these mesostructures to crystallization and
polymorphism of drugs, fats, and nutraceuticals and will discuss
regioselectivity of organic and enzymatic reactions that take
place at interfaces and within the channels of the mesophase. The book
will bring studies on the use of these mesophase as crystallization or
particulation media for the formation of nanoparticles and
nanocrystals. Chapters will discuss applications in the areas of
pharmaceuticals, food, cosmetics, plastics, paper, agro-chemistry and
industrial applications.
Nissim Garti, PhD, is the Ratner Honor Chair of Chemistry,
member of the management committee of The Hebrew University of
Jerusalem and the head of the Formulation Center of the Department of
Chemistry, and advisor to several global companies. He established
Adumim Chemicals' Nutraceutical Systems (Nutralease) and Delivery
Lyotropic Systems (DLS).
PONISSERIL SOMASUNDARAN, is the Director of the
Industry/University Cooperative Research Center for Advanced Studies
in Novel Surfactants at Columbia University. His research examines
surface and colloid chemistry of minerals, materials and microbes,
molecular interactions at surfaces, and environmental engineering.
RAFFAELE MEZZENGA is Full Professor at ETH Zürich. His research
focuses on self-assembly processes in liquid crystalline polymers,
supramolecular polymers, lyotropic liquid crystals, and biological and
food colloidal systems. He is a recipient of several international
awards in the field of soft condensed matter, including the John H.
Dillon Medal of the American Physical Society.
