Book description
This book focuses on the drug discovery and development applications of
transition metal catalyzed processes, which can efficiently create
preclinical and clinical drug candidates as well as marketed drugs. The
authors pay particular attention to the challenges of transitioning
academically-developed reactions into scalable industrial processes.
Additionally, the book lays the groundwork for how continued development
of transition metal catalyzed processes can deliver new drug candidates.
This work provides a unique perspective on the applications of
transition metal catalysis in drug discovery and development - it is a
guide, a historical prospective, a practical compendium, and a source of
future direction for the field.
MATTHEW L. CRAWLEY, PhD, is the Director of the Community
Physician Electronic Medical Records Program at Main Line Health.
Previously, he has worked as a medicinal chemist at Pfizer and Wyeth
Research. Dr. Crawley is an author of more than twenty publications,
and his discoveries have resulted in several patents.
BARRY M. TROST, PhD, is Tamaki Professor of Humanities and
Sciences in the Department of Chemistry at Stanford University. Dr.
Trost has been elected a Fellow of the American Academy of Sciences
and member of the National Academy of Sciences. He has served as
chairman of the NIH Medicinal Chemistry Study Section, held over 120
university lectureships, and presented over 260 plenary lectures at
national and international meetings.
