Book description
The definitive guide to mass spectrometry techniques in biology and biophysics
The use of mass spectrometry (MS) to study the architecture and
dynamics of proteins is increasingly common within the biophysical
community, and Mass Spectrometry in Structural Biology and Biophysics:
Architecture, Dynamics, and Interaction of Biomolecules, Second
Edition provides readers with detailed, systematic coverage of the
current state of the art.
Offering an unrivalled overview of modern MS-based armamentarium that
can be used to solve the most challenging problems in biophysics,
structural biology, and biopharmaceuticals, the book is a practical
guide to understanding the role of MS techniques in biophysical
research. Designed to meet the needs of both academic and industrial
researchers, it makes mass spectrometry accessible to professionals in
a range of fields, including biopharmaceuticals.
This new edition has been significantly expanded and updated to
include the most recent experimental methodologies and techniques, MS
applications in biophysics and structural biology, methods for
studying higher order structure and dynamics of proteins, an
examination of other biopolymers and synthetic polymers, such as
nucleic acids and oligosaccharides, and much more.
Featuring high-quality illustrations that illuminate the concepts
described in the text, as well as extensive references that enable the
reader to pursue further study, Mass Spectrometry in Structural
Biology and Biophysics is an indispensable resource for researchers
and graduate students working in biophysics, structural biology,
protein chemistry, and related fields.
IGOR A. KALTASHOV, PHD, is a Professor in the Department of
Chemistry at the University of Massachusetts Amherst.
STEPHEN J. EYLES, PHD, is a Senior Lecturer in the Department
of Biochemistry and Molecular Biology, and the Director of the Mass
Spectrometry Center at the University of Massachusetts Amherst.
