Book description
A comprehensive, authoritative look at an emergent area in post-genomic
science, Evolutionary genomics is an up-and-coming, complex field that
attempts to explain the biocomplexity of the living world.
Evolutionary Genomics and Systems Biology
is the first full-length book to blend established and emerging
concepts in bioinformatics, evolution, genomics, and structural biology,
with the integrative views of network and systems biology.
Three key
aspects of evolutionary genomics and systems biology are covered in
clear detail: the study of genomic history, i. e., understanding
organismal evolution at the genomic level; the study of macromolecular
complements, which encompasses the evolution of the protein and RNA
machinery that propels life; and the evolutionary and dynamic study of
wiring diagrams-macromolecular components in interaction-in the
context of genomic complements. The book also features:
- A solid, comprehensive treatment of phylogenomics, the evolution
of genomes, and the evolution of biological networks, within the
framework of systems biology
- A special section on RNA biology-translation, evolution of
structure, and micro RNA and regulation of gene expression
- Chapters on the mapping of genotypes to phenotypes, the role of
information in biology, protein architecture and biological
function, chromosomal rearrangements, and biological networks and disease
- Contributions by leading authorities on each topic
Evolutionary Genomics and Systems Biology is an ideal book for
students and professionals in genomics, bioinformatics, evolution,
structural biology, complexity, origins of life, systematic biology,
and organismal diversity, as well as those individuals interested in
aspects of biological sciences as they interface with chemistry,
physics, and computer science and engineering.
Gustavo Caetano-Anollés, PhD, is Professor in the
Department of Crop Sciences at the University of Illinois in
Urbana-Champaign, Illinois. He has more than 150 well-cited original
research publications in areas related to DNA technology and genomics,
and holds half a dozen US patents in various areas of DNA science and
biotechnology. His successful book, DNA Markers: Protocols,
Applications, and Overviews, was published by Wiley in 1997.
