Book description
The latest edition of the authoritative reference to HPLC
High-performance liquid chromatography (HPLC) is today the leading
technique for chemical analysis and related applications, with an
ability to separate, analyze, and/or purify virtually any sample.
Snyder and Kirkland's Introduction to Modern Liquid
Chromatography has long represented the premier reference to HPLC.
This Third Edition, with John Dolan as added coauthor,
addresses important improvements in columns and equipment, as well as
major advances in our understanding of HPLC separation, our ability to
solve problems that were troublesome in the past, and the application
of HPLC for new kinds of samples.
This carefully considered Third Edition maintains the
strengths of the previous edition while significantly modifying its
organization in light of recent research and experience. The text
begins by introducing the reader to HPLC, its use in relation to other
modern separation techniques, and its history, then leads into such
specific topics as:
- The basis of HPLC separation and the general effects of
different experimental conditions
- Equipment and detection
- The column-the "heart" of the HPLC system
- Reversed-phase separation, normal-phase chromatography, gradient
elution, two-dimensional separation, and other techniques
- Computer simulation, qualitative and quantitative analysis, and
method validation and quality control
- The separation of large molecules, including both biological and
synthetic polymers
- Chiral separations, preparative separations, and sample preparation
- Systematic development of HPLC separations-new to this edition
- Troubleshooting tricks, techniques, and case studies for both
equipment and chromatograms
Designed to fulfill the needs
of the full range of HPLC users, from novices to experts,
Introduction to Modern Liquid Chromatography, Third Edition
offers the most up-to-date, comprehensive, and accessible survey of
HPLC methods and applications available.
Lloyd R. Snyder, PhD, is a Principal at LC
Resources in Walnut Creek, California. He is the author or coauthor of
several books including An Introduction to Separation Science,
Introduction to Modern Liquid Chromatography, Second Edition, the
bestselling Practical HPLC Method Development, Second Edition, and the
comprehensive High-Performance Gradient Elution, all published by Wiley.
Joseph J. Kirkland, PhD, is Vice President of Research and
Development for Advanced Materials Technology, Inc., and coauthor of
Introduction to Modern Liquid Chromatography, Second Edition,
Practical HPLC Method Development, Second Edition, and Modern
Size-Exclusion Liquid Chromatography, Second Edition, all published by Wiley.
John W. Dolan, PhD, is a Principal at LC Resources. He is
author of the popular "LC Troubleshooting" column in LCGC
magazine and coauthor with Lloyd Snyder of Troubleshooting LC Systems
and High-Performance Gradient Elution.
