Book description
This book provides up-to-date information on experimental and
computational characterization of the structural and functional
properties of viral proteins, which are widely involved in regulatory
and signaling processes. With chapters by leading research groups, it
features current information on the structural and functional roles of
intrinsic disorders in viral proteomes. It systematically addresses the
measles, HIV, influenza, potato virus, forest virus, bovine virus,
hepatitis, and rotavirus as well as viral genomics. After analyzing the
unique features of each class of viral proteins, future directions for
research and disease management are presented.
VLADIMIR N. UVERSKY is an Associate Professor at the Department of
Molecular Medicine at the University of South Florida (USF). He
obtained his academic degrees from Moscow Institute of Physics and
Technology (PhD in 1991) and from the Institute of Experimental and
Theoretical Biophysics, Russian Academy of Sciences (DSc in 1998). He
spent his early career working mostly on protein folding at the
Institute of Protein Research and Institute for Biological
Instrumentation, Russia. In 1998, he moved to the University of
California Santa Cruz where for six years he was studying protein
folding, misfolding, protein conformation diseases, and protein
intrinsic disorder phenomenon. In 2004, he was invited to join the
Indiana University School of Medicine as a Senior Research Professor
to work on intrinsically disordered proteins. Since 2010, Professor
Uversky is with USF, where he continues to study intrinsically
disordered proteins and protein folding and misfolding processes. He
has authored over 400 scientific publications and edited several books
and book series on protein structure, function, folding and misfolding.
SONIA LONGHI is a Director of Research at the Center for the National
Scientific Research (CNRS). She obtained her academic degree (PhD)
from the University of Milan in 1993. She then went to the
Architecture and Function of Biological Macromolecules laboratory
(AFMB, UMR 6098, CNRS and Aix-Marseille University) where she did
postdoctoral work on protein crystallography. Since 2006, she has been
heading the "Structural Disorder and Molecular Recognition"
group within the AFMB laboratory. She has authored more than 70
scientific publications and edited a book on measles virus
nucleoprotein and coedited, with Prof. Vladimir Uversky, a book
entitled Instrumental Analysis of Intrinsically Disordered Proteins
(Wiley).
