Book description
Complete, up-to-date coverage of the broad area of nucleic acid
chemistry and biology
Assembling contributions from a collection of authors with expertise
in all areas of nucleic acids, medicinal chemistry, and therapeutic
applications, Medicinal Chemistry of Nucleic Acids presents a
thorough overview of nucleic acid chemistry-a rapidly evolving and
highly challenging discipline directly responsible for the development
of antiviral and antitumor drugs. This reliable resource delves into a
multitude of subject areas involving the study of nucleic acids-such
as the new advances in genome sequencing, and the processes for
creating RNA interference (RNAi) based drugs-to assist pharmaceutical
researchers in removing roadblocks that hinder their ability to
predict drug efficacy. Offering the latest cutting-edge science in
this growing field, Medicinal Chemistry of Nucleic Acids includes:
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In-depth coverage of the development and application of
modified nucleosides and nucleotides in medicinal chemistry
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A close look at a large range of current topics on nucleic acid
chemistry and biology
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Essential information on the use of nucleic acid drugs to treat
diseases like cancer
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A thorough exploration of siRNA for RNAi and the regulation of
microRNA, non-coding RNA (ncRNA), a newly developing and
exciting research area
Thorough in its approach and promising in its message, Medicinal
Chemistry of Nucleic Acids probes the new domains of
pharmaceutical research-and exposes readers to a wealth of new drug
discovery opportunities emerging in the dynamic field of nucleic acid
chemistry.
LI-HE ZHANG is President of the academic committee
of State Key Laboratory of Natural and Biomimetic Drugs, as well as
Professor of Medicinal Chemistry at Peking University. He is also a
member of the Chinese Academy of Sciences, Fellow of the Royal Society
of Chemistry, former vice president of the Chinese Pharmaceutical
Association, and past president of the Asian Federation of Medicinal Chemistry.
ZHEN XI, PhD, is Deputy Director of the State Key Laboratory of
Elemento-organic Chemistry, as well as Professor of Pesticide Science
and Chemical Biology, and Vice Dean of the College of Chemistry at
Nankai University. He holds seven patents and has written a number of
reviews and book chapters and sixty-four original research articles.
JYOTI CHATTOPADHYAYA, PhD, DSc, is the University Chair of
Bioorganic Chemistry and the chair of the Chemical Biology Program at
Uppsala University. He is a guest professor of chemistry at both Jilin
University and Nankai University. He has written over 410
peer-reviewed original research articles and is also on the editorial
boards of several international journals.
