Book description
Enables you to detect, identify, and characterize hundreds of drugs
that may be used by athletes
Mass spectrometry has become essential to sports drug testing. This
book examines both the principles of sports drug testing and the use
of mass spectrometry techniques and mass spectral data to detect,
identify, and characterize hundreds of known and unknown drugs that
athletes may use to enhance their performance. The author provides a
detailed overview of the mass spectrometry of numerous classes of
therapeutics and agents, various analyzers to detect low- and
high-molecular weight drugs, as well as techniques to discriminate
between endogenously produced and synthetically derived compounds.
Mass Spectrometry in Sports Drug Testing begins with a full
chapter dedicated to the history of sports drug testing. Next, the
book provides the principles and techniques needed to maximize the
specificity and sensitivity of mass spectrometric assays, including:
- Detailed, step-by-step assays with sample preparation
- Discussion of both chromatographic separation and mass
spectrometric analysis
- Characterization of analytes in order to unequivocally identify
banned substances
- Mass spectrometric behavior of low- and high-molecular weight analytes
Throughout the book, descriptive examples illustrate the principles,
advantages, and limitations of different assays.
Mass Spectrometry in Sports Drug Testing not only sets forth
the role mass spectrometry plays in detecting drug use among athletes,
it also adds new insights into the health and ethical issues of doping
in sports.
Mario Thevis, PhD, is Professor for Preventive
Doping Research at the German Sport University Cologne. He has
published more than 115 articles in peer-reviewed journals, mainly on
mass spectrometry and sports drug testing. Dr. Tevis is often invited
to national and international conferences as a speaker and keynote
lecturer on mass spectrometry and doping controls.