Book description
This book provides a timely overview of toxicogenomics, with special
emphasis on the practical applications of this technology to the risk
assessment process. Introductory sections are followed by a series of
chapters highlighting practical and systematic applications of
toxicogenomics in informing the risk assessment process - including the
areas of mutagenicity, carcinogenicity, endocrine toxicity,
organ-specific toxicity, population monitoring, and ecotoxicology. The
book concludes with approaches for the integration of this technology in
safety evaluation studies, and an outlook on how toxicogenomics and
complementary technologies can reframe the current risk assessment
paradigm.
DARRELL R. BOVERHOF
, PhD, is a Senior Toxicology Specialist at The Dow Chemical Company
where he leads research programs on respiratory allergy and
sensitization, nanotoxicology, and toxicogenomics. Dr. Boverhof has
authored or coauthored numerous peer-reviewed publications, review
articles, and book chapters in the area of toxicogenomics and serves on
the editorial board of the journal Toxicological Sciences.
B. BHASKAR GOLLAPUDI, PhD, is the Scientific Director of
Mammalian Toxicology at The Dow Chemical Company's Global Toxicology
& Environmental Research Laboratory. Dr. Gollapudi has authored or
co-authored more than 80 scientific publications. He is an Associate
Editor of the journal Toxicological Sciences and is currently serving
as an adjunct Associate Professor of Toxicology in the Department of
Public Health at the University of Michigan.
