Book description
This book grew out of an online interactive offered through
statcourse. com
, and it soon became apparent to the author that the course was too
limited in terms of time and length in light of the broad backgrounds of
the enrolled students. The statisticians who took the course needed to
be brought up to speed both on the biological context as well as on the
specialized statistical methods needed to handle large arrays.
Biologists and physicians, even though fully knowledgeable concerning
the procedures used to generate microaarrays, EEGs, or MRIs, needed a
full introduction to the resampling methods-the bootstrap, decision
trees, and permutation tests, before the specialized methods applicable
to large arrays could be introduced. As the intended audience for this
book consists both of statisticians and of medical and biological
research workers as well as all those research workers who make use of
satellite imagery including agronomists and meteorologists, the book
provides a step-by-step approach to not only the specialized methods
needed to analyze the data from microarrays and images, but also to the
resampling methods, step-down multi-comparison procedures, multivariate
analysis, as well as data collection and pre-processing. While many
alternate techniques for analysis have been introduced in the past
decade, the author has selected only those techniques for which software
is available along with a list of the available links from which the
software may be purchased or downloaded without charge. Topical coverage
includes: very large arrays; permutation tests; applying permutation
tests; gathering and preparing data for analysis; multiple tests;
bootstrap; applying the bootstrap; classification methods; decision
trees; and applying decision trees.
Phillip I. Good, PhD, is
Operations Manager at Information Research, a consulting firm
specializing in statistical solutions for private and public
organizations. He has published more than thirty scholarly works and
more than six hundred popular articles. Dr. Good is the author of
Introduction to Statistics Through Resampling Methods and R/S-PLUS®
and Introduction to Statistics Through Resampling Methods and
Microsoft Office Excel®, and coauthor of Common Errors in Statistics
(and How to Avoid Them), Third Edition, all published by Wiley.